Chapters 7, 8, and 9 describe the general tactics employed in developing an effective drug and also the difficulties faced by the medicinal chemist in this task. No previous knowledge of biology is assumed and the first six chapters cover the basics of cell structure, proteins, and nucleic acids as applied to drug design. It attempts to convey something of the fascination of working in a field which overlaps the disciplines of chemistry, biochemistry, cell biology, and pharmacology.
This text is aimed at undergraduates who have a basic grounding in chemistry and are interested in a future career in the pharmaceutical industry. RS403.P38 1995 615/.19-dc20 94-24704 ISBN 0 19 855872 4 (Hbk) ISBN 0 19 855871 6 (Pbk) Typeset by Footnote Graphics, Warminster, Wilts Printed in Great Britain on acid-free paper by the Bath Press Includes bibliographical references and index. An introduction to medicinal chemistry I Graham L. A catalogue record for this book is available from the British Library Library of Congress Cataloging in Publication Data Patrick, Graham L. This book is sold subject to the condition that it shall not, by way of trade or otherwise, be lent, re-sold, hired out, or otherwise circulated without the publisher's prior consent in any form of binding or cover other than that in which it is published and without a similar condition including this condition being imposed on the subsequent purchaser.
Enquiries concerning reproduction outside these terms and in other countries should be sent to the Rights Department, Oxford University Press, at the address above. Within the UK, exceptions are allowed in respect of any fair dealing for the purpose of research or private study, or criticism or review, as permitted under the Copyright, Designs and Patents Act, 1988, or in the case of reprographic reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency.
No pan of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without the prior permission in uniting of Oxford University Press. Oxford University Press, Walton Street, Oxford OX2 6DP Oxford New York Athens Auckland Bangkok Bombay Calcutta Cape Town Dar es Salaam Delhi Florence Hong Kong Istanbul Karachi Kuala Lumpur Madras Madrid Melbourne Mexico City Nairobi Paris Singapore Taipei Tokyo Toronto and associated companies in Berlin Ibadan Oxford is a trade mark of Oxford University Press Published in the United States by Oxford University Press Inc., New York © Graham L. Oxford New York Tokyo OXFORD U N I V E R S I T Y PRESS 1995 PATRICK Department of Chemistry, Paisley University An Introduction to Medicinal Chemistry GRAHAM L.
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